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CD4 Antikörper

Der Ratte Monoklonal Anti-CD4-Antikörper wurde für FACS und IHC (fro) validiert. Er ist geeignet, CD4 in Proben von Maus zu detektieren.
Produktnummer ABIN319535

Kurzübersicht für CD4 Antikörper (ABIN319535)

Target

Alle CD4 Antikörper anzeigen
CD4

Reaktivität

  • 423
  • 271
  • 140
  • 48
  • 30
  • 24
  • 22
  • 20
  • 17
  • 12
  • 11
  • 11
  • 11
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Maus

Wirt

  • 449
  • 175
  • 155
  • 7
  • 3
  • 3
  • 1
  • 1
Ratte

Klonalität

  • 645
  • 141
  • 5
Monoklonal

Konjugat

  • 234
  • 77
  • 66
  • 52
  • 44
  • 20
  • 15
  • 14
  • 12
  • 11
  • 11
  • 11
  • 9
  • 7
  • 6
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
Dieser CD4 Antikörper ist unkonjugiert

Applikation

  • 650
  • 211
  • 152
  • 120
  • 96
  • 85
  • 72
  • 57
  • 43
  • 41
  • 39
  • 30
  • 17
  • 12
  • 9
  • 9
  • 8
  • 7
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon

YTS191-1
  • Spezifität

    This antibody recognises the CD4 cell surface antigen, expressed by a subset of T-lymphocytes. This clone exhibits depleting activity when used in vivo (Antibody SM005LE is recommended for this purpose).

    Aufreinigung

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    Isotyp

    IgG2b
  • Applikationshinweise

    Flow Cytometry: use 10 μL of 1/50-1/100 diluted antibody to label 10^6 cells. Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4, with 0.09 % sodium azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    CD4

    Andere Bezeichnung

    CD4

    Hintergrund

    CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

    Gen-ID

    12504

    NCBI Accession

    NP_038516

    UniProt

    P06332

    Pathways

    T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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