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Integrin beta 3 Antikörper (PE)

Der Maus Monoklonal Anti-Integrin beta 3-Antikörper wurde für FACS validiert. Er ist geeignet, Integrin beta 3 in Proben von Human zu detektieren.
Produktnummer ABIN319520

Kurzübersicht für Integrin beta 3 Antikörper (PE) (ABIN319520)

Target

Alle Integrin beta 3 (ITGB3) Antikörper anzeigen
Integrin beta 3 (ITGB3)

Reaktivität

  • 253
  • 103
  • 70
  • 17
  • 15
  • 13
  • 13
  • 11
  • 8
  • 8
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 157
  • 102
  • 16
  • 2
  • 2
Maus

Klonalität

  • 155
  • 122
Monoklonal

Konjugat

  • 137
  • 18
  • 16
  • 11
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser Integrin beta 3 Antikörper ist konjugiert mit PE

Applikation

  • 142
  • 120
  • 102
  • 52
  • 50
  • 38
  • 31
  • 26
  • 25
  • 20
  • 15
  • 13
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

Y2-51
  • Aufreinigung

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    Immunogen

    PHA stimulated peripheral blood cells. Spleen cells from immunised Balb/c mice were fused with cells of the NS1 myeloma cell line.

    Isotyp

    IgG1
  • Applikationshinweise

    Flow Cytometry: use 10 μL of neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Rekonstitution

    Restore with 1.0 mL distilled water.

    Konzentration

    0.1mg/mL

    Buffer

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Dilute only prior to immediate use

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
  • Target

    Integrin beta 3 (ITGB3)

    Andere Bezeichnung

    CD61 / ITGB3

    Hintergrund

    CD61 is a 105kD glycoprotein, which is also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa

    Gen-ID

    9606

    UniProt

    P05106

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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