Integrin beta 3 Antikörper
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- Target Alle Integrin beta 3 (ITGB3) Antikörper anzeigen
- Integrin beta 3 (ITGB3)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Immunogen
- PHA stimulated peripheral blood cells. Spleen cells from immunised Balb/c mice were fused with cells of the NS1 myeloma cell line.
- Klon
- Y2-51
- Isotyp
- IgG1
- Top Product
- Discover our top product ITGB3 Primärantikörper
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- Applikationshinweise
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Flow Cytometry: use 10 μL of 1/100-1/200 diluted antibody to label 10^6 cells in 100 μL. Immunohistochemistry on Frozen and Paraffin Sections: This product requires proteindigestion pre-treatment of paraffin sections e. g. trypsin prior to staining. Western Blotting: Detects a band/s of approximately 90 kDa in platelet lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Integrin beta 3 (ITGB3)
- Andere Bezeichnung
- CD61 / ITGB3 (ITGB3 Produkte)
- Hintergrund
- CD61 is a 105kD glycoprotein, which is also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
- Gen-ID
- 9606
- UniProt
- P05106
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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