AMBP Antikörper

Produktnummer ABIN319500

Der Schaf Polyklonal anti-AMBP Antikörper (ABIN319500) detektiert spezifisch AMBP in EIA und ID. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für AMBP Antikörper (ABIN319500)

Target: AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser AMBP Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunodiffusion (ID)

Produktdetails anti-AMBP Antikörper

Spezifität: This antibody recognises human alpha-1-Microglobulin. No cross-reactivity is observed with Urine Albumin, Retinol binding protein or beta-2-Microglobulin. It does Not react with Rat.

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Highly pure human alpha-1-microglobulin, prepared from the urine of patients with chronic renal proteinuria (Molecular Weight 25-30 kD).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA (1/500-1/1000). Immunodiffusion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 5.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu AMBP

Target: AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))

Andere Bezeichnung: AMBP

Hintergrund: Alpha(1)microglobulin/bikunin precursor specifically interacts with the ORF3 protein of hepatitis E virus and has a direct role in enhancing alpha(1)microglobulin export from the hepatocyte. Bikunin has a role in downregulating PI3 kinase and suppressing tumor invasiveness and metastasis in ovaran cancer cells. I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. Interacts with FN1Synonyms: Alpha-1 microglycoprotein, Alpha-1-microglobulin, Bikunin, Complex-forming glycoprotein heterogeneous in charge, EDC1, HCP, HI-30, ITI-LC, ITIL, Inter-alpha-trypsin inhibitor light chain, Trypstatin, Uronic-acid-rich protein

Gen-ID: 259

NCBI Accession: NP_001624

UniProt: P02760