Dynamin 1 Antikörper (pSer778)
Kurzübersicht für Dynamin 1 Antikörper (pSer778) (ABIN319106)
Target
Alle Dynamin 1 (DNM1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer778
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Spezifität
- This antibody is specific for Dynamin when phosphorylated at serine 778.
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Aufreinigung
- Affinity chromatography
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Immunogen
- Synthetic phosphopeptide corresponding to an amino acid sequence within dynamin which includes phosphorylated Ser778.
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Isotyp
- IgG
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Applikationshinweise
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Western Blot: 1: 1000, detects a band of approximately 95 kDa in rat hippocampus lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Dynamin 1 (DNM1)
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Andere Bezeichnung
- Dynamin-1
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Hintergrund
- Dynamin is a phosphoprotein expressed at nerve terminals, which plays an important role in the regulation of synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 (cdk5) has been shown to phosphorylate serine 774 and 778 in vivo. Dephosphorylation of these residues is essential for endocytosis of synaptic vesicles.Synonyms: DNM, DNM1
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Gen-ID
- 140694
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NCBI Accession
- NP_542420
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UniProt
- P21575
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Pathways
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
Target
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