RNF34 Antikörper (N-Term)

Produktnummer ABIN318868

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RNF34 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund und Primate.

Kurzübersicht für RNF34 Antikörper (N-Term) (ABIN318868)

Target: RNF34 (Ring Finger Protein 34 (RNF34))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF34 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-RNF34 Antikörper

Bindungsspezifität: AA 1-373, N-Term

Spezifität: This antibody detects Ring Finger homologous to Inhibitor of apoptosis protein (hRFI).

Aufreinigung: Purified

Immunogen: Recombinant protein corresponding to amino acids 1-373 of human RFI.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1800 - 1: 4000. Western Blot: 1: 100 - 1: 600, detects a band of approximately 42 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RNF34

Target: RNF34 (Ring Finger Protein 34 (RNF34))

Andere Bezeichnung: RFI / RNF34

Hintergrund: RFI is an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL. It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation. hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm. hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers.Synonyms: CARP-1, CARP1, Caspases-8 and -10-associated RING finger protein 1, E3 ubiquitin-protein ligase RNF34, FYVE-RING finger protein Momo, Human RING finger homologous to inhibitor of apoptosis protein, RIFF

Gen-ID: 80196

NCBI Accession: NP_079402

UniProt: Q969K3