PPARD Antikörper (N-Term)

Produktnummer ABIN318837

Der Kaninchen Polyklonal anti-PPARD Antikörper (ABIN318837) detektiert spezifisch PPARD in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen und Affe.

Kurzübersicht für PPARD Antikörper (N-Term) (ABIN318837)

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Reaktivität: Human, Maus, Ratte, Kaninchen, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-PPARD Antikörper

Bindungsspezifität: AA 1-14, N-Term

Spezifität: This antibody detects peroxisome proliferator-activated receptor, delta (PPARD).

Aufreinigung: Purified

Immunogen: Syntetic peptide corresponding to amino acids 1-14 of mouse PPAR delta.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 2000 - 1: 8000. Western Blot: 1: 500 - 1: 2000, detects a band of approximately 55 kDa in heart whole celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PPARD

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Andere Bezeichnung: PPAR-delta

Hintergrund: PPARD is a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta. PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis.Synonyms: NR1C2, NUCI, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2, PPAR-beta, PPARB, PPARD, Peroxisome proliferator-activated receptor delta

Gen-ID: 19015

NCBI Accession: NP_035275

UniProt: P35396

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation