TNNI3 Antikörper

Produktnummer ABIN318833

Produktdetails anti-TNNI3 Antikörper

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TNNI3 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Spezifität: This antibody recognises human cardiac-specific troponin I, (TnI) an integral inhibitory protein of cardiac muscle which exists as a complex with troponin C (TnC) and troponin T (TnT).

Aufreinigung: Purified IgG prepared by Immunoaffinity chromatography

Immunogen: Native human cardiac troponin I, purity greater than 98%.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: PBS buffer pH 7.4 containing 0.09 % Sodium Azide (NaN3)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TNNI3

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Andere Bezeichnung: Cardiac Troponin I (TNNI3 Produkte)

Synonyme: CMD1FF antikoerper, CMD2A antikoerper, CMH7 antikoerper, RCM1 antikoerper, TNNC1 antikoerper, cTnI antikoerper, CMD1Z antikoerper, CMH13 antikoerper, TN-C antikoerper, TNC antikoerper, TNNC antikoerper, Tn1 antikoerper, TnIc antikoerper, ctnIc antikoerper, XTnIc antikoerper, c-troponin antikoerper, cTNT antikoerper, cmh7 antikoerper, ctni antikoerper, tnnc1 antikoerper, TNNI3 antikoerper, TnI antikoerper, cTNI antikoerper, AI874626 antikoerper, TnC antikoerper, cTnC antikoerper, tncc antikoerper, Tncc antikoerper, troponin I3, cardiac type antikoerper, troponin C1, slow skeletal and cardiac type antikoerper, troponin I, cardiac 3 antikoerper, troponin I type 3 (cardiac) antikoerper, troponin I3, cardiac type S homeolog antikoerper, troponin I3, cardiac type L homeolog antikoerper, cardiac troponin I antikoerper, troponin C, cardiac/slow skeletal antikoerper, TNNI3 antikoerper, TNNC1 antikoerper, Tnni3 antikoerper, tnni3.S antikoerper, tnni3.L antikoerper, tnni3 antikoerper, LOC100462680 antikoerper, Tnnc1 antikoerper

Hintergrund: The TnT subunit of troponin binds to tropomyosin to form a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, enabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurement of blood TnI and TnT levels is an important diagnostic indicator of heart muscle damage, and can be used to differentiate between angina and myocardic infarction in patients with chest pain. Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro.Synonyms: TNNC1, TNNI3

Gen-ID: 7137

NCBI Accession: NP_000354

UniProt: P19429