TNNI3 Antikörper

Produktnummer ABIN318833

Der Ziege Polyklonal anti-TNNI3 Antikörper wird verwendet zum Nachweis von TNNI3 in Proben von Human. Er wurde validiert für EIA.

Kurzübersicht für TNNI3 Antikörper (ABIN318833)

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TNNI3 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Produktdetails anti-TNNI3 Antikörper

Spezifität: This antibody recognises human cardiac-specific troponin I, (TnI) an integral inhibitory protein of cardiac muscle which exists as a complex with troponin C (TnC) and troponin T (TnT).

Aufreinigung: Purified IgG prepared by Immunoaffinity chromatography

Immunogen: Native human cardiac troponin I, purity greater than 98%.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: PBS buffer pH 7.4 containing 0.09 % Sodium Azide (NaN3)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TNNI3

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Andere Bezeichnung: Cardiac Troponin I

Hintergrund: The TnT subunit of troponin binds to tropomyosin to form a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, enabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurement of blood TnI and TnT levels is an important diagnostic indicator of heart muscle damage, and can be used to differentiate between angina and myocardic infarction in patients with chest pain. Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro.Synonyms: TNNC1, TNNI3

Gen-ID: 7137

NCBI Accession: NP_000354

UniProt: P19429