Der Kaninchen Polyklonal anti-HAVCR1 Antikörper (ABIN318765) detektiert spezifisch HAVCR1 in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
This antibody detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified as the receptor used by hepatitis A for viral entry (it is also known as the hepatitis A virus cellular receptor- HAVCR).
Aufreinigung
Purified
Immunogen
16 amino acid peptide sequence near the centre of human TIM-1.
HAVCR1
Reaktivität: Human
WB, IHC, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Western Blot: 1.0 - 2.0g/mL, detects a band of approximately 49 kDa in human uterustissue lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target
HAVCR1
(Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
Andere Bezeichnung
TIMD1 / HAVCR1
Substanzklasse
Virus
Hintergrund
TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and T helper type 2 (Th2) cytokine production. TIM-1 has also been shown to bind and activate macrophages. Two splice variants for human TIM-1 exist, TIM-1a is predominantly expressed in the liver, whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to be upregulated in damaged tissue, and is thought to assist healing. TIM-1 polymorphisms are associated with asthma.Synonyms: HAVCR-1, Hepatitis A virus cellular receptor 1, T cell immunoglobulin and mucin domain-containing protein 1, T cell membrane protein 1, TIM-1, TIM1, TIMD-1