Ectodysplasin A2 Receptor Antikörper

Produktnummer ABIN318757

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Ectodysplasin A2 Receptor in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Ectodysplasin A2 Receptor Antikörper (ABIN318757)

Target: Ectodysplasin A2 Receptor (EDA2R)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ectodysplasin A2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Ectodysplasin A2 Receptor Antikörper

Spezifität: This antibody detects human X-linked ectodermal dysplasia receptor (XEDAR).

Aufreinigung: Purified

Immunogen: Recombinant human XEDAR.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5 - 2.0g/mL, detects a band of approximately 33 kDa in 293 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu Ectodysplasin A2 Receptor

Target: Ectodysplasin A2 Receptor (EDA2R)

Andere Bezeichnung: EDA2R / TNFRSF27

Hintergrund: XEDAR is a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist, XEDAR-s and XEDAR-L, produced by alternative splicing.Synonyms: EDA-A2 receptor, Tumor necrosis factor receptor superfamily member 27, UNQ2448/PRO5727/PRO34080, X-linked ectodysplasin-A2 receptor, XEDAR

Gen-ID: 60401

NCBI Accession: NP_001186616

UniProt: Q9HAV5