Cadherin 13 Antikörper (N-Term)

Produktnummer ABIN318711

Der Kaninchen Polyklonal anti-Cadherin 13 Antikörper (ABIN318711) detektiert spezifisch Cadherin 13 in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Cadherin 13 Antikörper (N-Term) (ABIN318711)

Target: Cadherin 13 (CDH13)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Cadherin 13 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody recognises T-Cadherin.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide corresponding to N-terminus of human Cadherin-13.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot (0.5-1.0 μg/mL): This antibody detects a band/s of approximately 78 kDa in3T3 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid multiple freeze/thaw cycles.

Details zu Cadherin 13

Target: Cadherin 13 (CDH13)

Andere Bezeichnung: Cadherin-13

Hintergrund: T-cadherin is a 78 kDa, calcium-dependent, glycoprotein. While T-cadherin is a member of the cadherin family, it lacks their conserved cytoplasmic region, being instead anchored to the plasma membrane via glycosylphosphatidylinositol linkage. It is expressed in the heart and CNS with the exception of the cerebellum and spinal cord. Cadherin 13 is classified as a cell-cell adhesion molecule, although it is likely that it's role is in signalling and not physical adhesion. It is involved in regulating low-density lipoprotein-initiated cell proliferation, keratinocyte proliferation, neural cell growth and may play a role in metabolic regulation. Cadherin 13 protects endothelial cells from oxidative stress-induced apoptosis and may contribute to progression of vascular disorders such as atherosclerosis, restenosis and tumour angiogenesis.Synonyms: CDH13, CDHH, Cadherin H, Cadherin T, H-Cadherin, Heart cadherin, P105, T-Cadherin, Truncated cadherin

Gen-ID: 1012

NCBI Accession: NP_001248

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization