Acetylcholinesterase Antikörper

Produktnummer ABIN318393

Dieses Anti-Acetylcholinesterase-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Acetylcholinesterase in WB und EIA. Geeignet für Human, Electric eel und Fisch.

Kurzübersicht für Acetylcholinesterase Antikörper (ABIN318393)

Target: Acetylcholinesterase (AChE)

Reaktivität: Human, Electric eel, Fisch

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetylcholinesterase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Acetylcholinesterase Antikörper

Kreuzreaktivität (Details): Species reactivity (expected):Human.
Species reactivity (tested):Electrophorus electricus (electric eel).

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Highly purified Acetylcholine Esterase from Electrophorus electricus.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/6K-1/24K. Western Blot: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 5.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Acetylcholinesterase

Target: Acetylcholinesterase (AChE)

Andere Bezeichnung: Acetylcholinesterase

Hintergrund: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.Synonyms: AChE, Acetylcholine Esterase, Acetylcholine-Esterase

Gen-ID: 8005

UniProt: O42275

Pathways: Skeletal Muscle Fiber Development