Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SNCA Antikörper (pSer129)

SNCA Reaktivität: Human, Ratte, Maus IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN318305
  • Target Alle SNCA Antikörper anzeigen
    SNCA (Synuclein, alpha (SNCA))
    Bindungsspezifität
    • 72
    • 31
    • 28
    • 24
    • 16
    • 15
    • 12
    • 11
    • 11
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer129
    Reaktivität
    • 294
    • 200
    • 200
    • 14
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 237
    • 100
    • 4
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 222
    • 123
    Polyklonal
    Konjugat
    • 146
    • 25
    • 22
    • 17
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    Dieser SNCA Antikörper ist unkonjugiert
    Applikation
    • 241
    • 165
    • 112
    • 80
    • 77
    • 68
    • 68
    • 52
    • 48
    • 43
    • 23
    • 21
    • 10
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects endogenous levels of SNCA protein only when phosphorylated at Ser129.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human and Mouse.
    Aufreinigung
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product SNCA Primärantikörper
  • Applikationshinweise
    ELISA: 1/1000-1/10000. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    SNCA (Synuclein, alpha (SNCA))
    Andere Bezeichnung
    alpha-Synuclein / SNCA (SNCA Produkte)
    Synonyme
    snca antikoerper, MGC64356 antikoerper, LOC619283 antikoerper, NACP antikoerper, alphaSYN antikoerper, PARK1 antikoerper, PARK4 antikoerper, PD1 antikoerper, synuclein alpha L homeolog antikoerper, alpha-synuclein antikoerper, synuclein alpha antikoerper, synuclein, alpha antikoerper, snca.L antikoerper, LOC619283 antikoerper, SNCA antikoerper, Snca antikoerper
    Hintergrund
    The synuclein family members, including α-synuclein (also designated NACP for non-β Amyloid component) and β-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-synuclein is localized to neuronal cell bodies and synapses. α-synuclein was first identified as a component of Alzheimer's disease amyloid plaques. Abnormal platelet function in Alzheimer's disease has been demonstrated. During megakaryocytic differentiation α-synuclein has been found to be upregulated, while β-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of α-synuclein has been found in patients with early onset Parkinson's disease.Synonyms: NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PARK1
    Molekulargewicht
    approx. 18 kDa
    Gen-ID
    6622
    NCBI Accession
    NP_000336
    UniProt
    P37840
    Pathways
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Sie sind hier:
Kundenservice