LIMK2 Antikörper (pThr505)

Produktnummer ABIN318064

Produktdetails anti-LIMK2 Antikörper

Target: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Bindungsspezifität: pThr505

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIMK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of LIMK2 pThr505 protein.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LIMK2

Target: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Andere Bezeichnung: LIMK2 (LIMK2 Produkte)

Synonyme: xlimk2 antikoerper, zgc:91990 antikoerper, wu:fa97c09 antikoerper, wu:fk73e11 antikoerper, LIMK2 antikoerper, Limk2b antikoerper, Link2 antikoerper, LIMK antikoerper, 9430059K01 antikoerper, A930024P04Rik antikoerper, C85310 antikoerper, Limk2a antikoerper, LIM domain kinase 2 L homeolog antikoerper, LIM domain kinase 2 antikoerper, LIM motif-containing protein kinase 2 antikoerper, limk2.L antikoerper, limk2 antikoerper, LIMK2 antikoerper, Limk2 antikoerper

Hintergrund: Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, incuding LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and Cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morpho-genesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and it is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.Synonyms: EC=2.7.11.1, LIM domain kinase 2, LIMK-2, LIMK2

Molekulargewicht: approx. 72 kDa

Gen-ID: 3985

NCBI Accession: NP_005560

UniProt: P53671