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ADCY4 Antikörper

ADCY4 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN317941
  • Target Alle ADCY4 Antikörper anzeigen
    ADCY4 (Adenylate Cyclase 4 (ADCY4))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 48
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADCY4 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 26
    • 13
    • 13
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    A Cyclase IV antibody detects endogenous levels of A Cyclase IV protein.(region surrounding Leu226)
    Aufreinigung
    Affinity chromatography
    Top Product
    Discover our top product ADCY4 Primärantikörper
  • Applikationshinweise
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ADCY4 (Adenylate Cyclase 4 (ADCY4))
    Andere Bezeichnung
    Adenylate Cyclase Type 4 (ADCY4 Produkte)
    Synonyme
    ADCY4 antikoerper, mKIAA4004 antikoerper, AC4 antikoerper, adenylate cyclase 4 antikoerper, ADCY4 antikoerper, Adcy4 antikoerper
    Hintergrund
    Adenylyl cyclases function to convert ATP to cyclic AMP in response to activation by a variety of hormones, neurotransmitters and other regulatory molecules. Cyclic AMP, in turn, activates several other target molecules to control a broad range of diverse phenomena such as metabolism, gene transcription and memory. Adenylyl cyclases respond to receptor-initiated signals, mediated by the Gs and Gi heterotrimeric G proteins. The binding of an agonist to a Gs-coupled receptor catalyzes the exchange of GDP (bound to Gα s) for GTP, the dissociation of GTP-Gα s from Gβγ and Gα s-mediated activation of adenylyl cyclase. Adenylyl cyclase IV (AC IV) and IX mRNA are expressed in all kidney nephron segments. AC IV exhibits moderate staining in type II and type IV fibrocytes in rat cochlea and immunoreactivity is also observed in type I fibrocytes. Activation of the D2 dopaminergic and m4 muscarine receptors inhibits the activity of adenylyl cyclase isozymes I, V, VI and VIII, whereas type II, IV and VII are stimulated and type III is not affected.Synonyms: ADCY4, ATP pyrophosphate-lyase 4, Adenylate cyclase type IV, Adenylyl cyclase 4
    Molekulargewicht
    approx. 120 kDa
    Gen-ID
    196883
    NCBI Accession
    NP_001185497
    UniProt
    Q8NFM4
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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