KCNK1
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
KCNK1
(Potassium Channel Subfamily K Member 1 (KCNK1))
AI788889 antikoerper, TWIK-1 antikoerper, DPK antikoerper, HOHO antikoerper, K2P1 antikoerper, K2p1.1 antikoerper, KCNO1 antikoerper, TWIK1 antikoerper, Twik antikoerper, k2p1.1 antikoerper, twik-1 antikoerper, twik1 antikoerper, rabKCNK1 antikoerper, im:7150627 antikoerper, kcnk1 antikoerper, zgc:165664 antikoerper, potassium channel, subfamily K, member 1 antikoerper, potassium two pore domain channel subfamily K member 1 antikoerper, potassium channel, two pore domain subfamily K, member 1 L homeolog antikoerper, potassium channel, subfamily K, member 1a antikoerper, Kcnk1 antikoerper, KCNK1 antikoerper, kcnk1.L antikoerper, kcnk1a antikoerper
Hintergrund
K+ channels are divided into three subclasses, reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions, and include TASK, TREK, TRAAK and TWIK. TWIK-1 mRNA is expressed abundantly in brain and at lower levels in lung, kidney and skeletal muscle. The molecular weight of TWIK-1 in mouse brain is 40 kDa under reducing conditions. TWIK-2 shares low sequence homology with other mammalian family group members, and only 34 % homology with TWIK-1. Human TWIK-2 is expressed in pancreas, placenta and heart, while mouse TWIK-2 is expressed in liver. TWIK-2 is inhibited by intracellular, but not extracellular, acidification.Synonyms: HOHO1, Inward rectifying potassium channel protein TWIK-1, KCNK1, KCNO1, Potassium channel KCNO1, Potassium channel subfamily K member 1, TWIK1