CYB5R3 Antikörper

Produktnummer ABIN317921

Der Kaninchen Polyklonal anti-CYB5R3 Antikörper wird verwendet zum Nachweis von CYB5R3 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für CYB5R3 Antikörper (ABIN317921)

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYB5R3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CYB5R3 Antikörper

Spezifität: CYB5R3 antibody detects endogenous levels of CYB5R3 protein.(region surrounding Ile169)

Aufreinigung: Affinity Chromatography.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/40000approx. 1/60000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CYB5R3

Target: CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

Andere Bezeichnung: CYB5R3

Hintergrund: CYB5R3 (NADH-cytochrome b5, reductase 3, diaphorase 1) is a 301 amino acid protein encoded by the human gene CYB5R3. CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms. Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane,while isoform 2 is the soluble form found in erythrocytes. CYB5R3 is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis,drug metabolism and, in erythrocytes, methemoglobin reduction. A serine residue at position 117 seems to only be found in persons of African origin. The allele frequency is 0.23 in African Americans. It is not found in Caucasians,Asians, Indo-Aryans or Arabs. This difference seems to have no effect on the enzyme activity.Synonyms: B5R, DIA1, Diaphorase-1, NADH-cytochrome b5 reductase 3

Molekulargewicht: approx. 34 kDa

Gen-ID: 1727

NCBI Accession: NP_000389

UniProt: P00387

Pathways: SARS-CoV-2 Protein Interaktom