ADRB3 Antikörper

Produktnummer ABIN317855

Der Kaninchen Polyklonal Anti-ADRB3-Antikörper wurde für WB validiert. Er ist geeignet, ADRB3 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für ADRB3 Antikörper (ABIN317855)

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ADRB3 Antikörper

Spezifität: AR-β3 antibody detects endogenous levels of AR-β3 protein.(region surrounding Leu291)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ADRB3

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Andere Bezeichnung: beta-3 Adrenergic Receptor

Hintergrund: The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. β-adrenergic bound to adrenaline activates adenylyl cyclase, while α2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the α2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories and they are designated 5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT5, 5-HT6 and 5-HT7. The 5-HT1 receptors have further been subdivided into 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D, 5-HT1E and 5-HT1F receptors.Synonyms: ADRB3, ADRB3R, B3AR, Beta-3 adrenoceptor

Molekulargewicht: approx. 36 kDa

Gen-ID: 155

NCBI Accession: NP_000016

UniProt: P13945

Pathways: cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation