PAQR7 Antikörper

Produktnummer ABIN317756

Der Kaninchen Polyklonal anti-PAQR7 Antikörper wird verwendet zum Nachweis von PAQR7 in Proben von Human. Er wurde validiert für WB und IF.

Kurzübersicht für PAQR7 Antikörper (ABIN317756)

Target: PAQR7 (Progestin and AdipoQ Receptor Family Member VII (PAQR7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAQR7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-PAQR7 Antikörper

Spezifität: MPRα antibody detects endogenous levels of mPRα protein.

Aufreinigung: Affinity chormatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PAQR7

Target: PAQR7 (Progestin and AdipoQ Receptor Family Member VII (PAQR7))

Hintergrund: The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated α, β and γ, comprise this gene family. mPRα, also designated progestin and adipoQ receptor family member VII (PAQR7), consists of an extracellular N-terminus, an intracellular C-terminus, and seven transmembrane domains. It is expressed in ovary, testis, placenta, uterus and bladder. mPRβ, also designated progestin and adipoQ receptor family member VIII (PAQR8), consists of eight putative transmembrane regions and an intracellular N-terminus that contains a leucine-rich motif. It is a 354 amino acid protein with a molecular mass of about 40 kDa and is expressed in brain and spinal cord. Both mPRα and mPRβ may be G protein-coupled receptors and may be involved in oocyte maturation.Synonyms: Membrane progestin receptor alpha, Progestin and adipoQ receptor family member 7, Progestin and adipoQ receptor family member VII, mPR alpha

Molekulargewicht: approx. 40 kDa

Gen-ID: 164091

NCBI Accession: NP_848509

UniProt: Q86WK9