MC5 Receptor Antikörper

Produktnummer ABIN317755

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MC5 Receptor in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MC5 Receptor Antikörper (ABIN317755)

Target: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MC5 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-MC5 Receptor Antikörper

Spezifität: MC5-R antibody detects endogenous levels of MC5-R protein. (region surrounding Glu308)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MC5 Receptor

Target: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Andere Bezeichnung: MC5-R

Hintergrund: The melanocortin family comprises the α-, β- and γ-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane, G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.Synonyms: MC-2, MC5R, Melanocortin receptor 5

Molekulargewicht: approx. 40 kDa

Gen-ID: 4161

NCBI Accession: NP_005904

UniProt: P33032

Pathways: cAMP Metabolic Process