GRM7 Antikörper

Produktnummer ABIN317753

Der Kaninchen Polyklonal anti-GRM7 Antikörper wird verwendet zum Nachweis von GRM7 in Proben von Human, Ratte und Maus. Er wurde validiert für WB und IF.

Kurzübersicht für GRM7 Antikörper (ABIN317753)

Target: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRM7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-GRM7 Antikörper

Spezifität: MGluR7 antibody detects endogenous levels of mGluR7 protein.(region surrounding Lys389)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GRM7

Target: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Andere Bezeichnung: mGluR7 / GRM7

Hintergrund: L glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups. Group III receptors include GRM7 and are linked to the inhibition of the cyclic AMP cascade. GRM7 has been reported to be expressed in active zones of presynaptic axon terminals in various regions of the brain, eye, and spinal cord.Synonyms: GPRC1G, MGLUR7, Metabotropic glutamate receptor 7

Molekulargewicht: approx. 102 kDa

Gen-ID: 2917

NCBI Accession: NP_000835

UniProt: Q14831

Pathways: Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour