S1PR3 Antikörper

Produktnummer ABIN317744

Der Kaninchen Polyklonal Anti-S1PR3-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, S1PR3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für S1PR3 Antikörper (ABIN317744)

Target: S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-S1PR3 Antikörper

Spezifität: This antibody detects endogenous levels of EDG-3 protein.(region surrounding Phe155)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity-chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/40000-1/60000. Wetren blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu S1PR3

Target: S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

Andere Bezeichnung: EDG-3 / S1P3

Hintergrund: EDG3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG3 is expressed in heart, placenta, kidney, and liver tissue.Synonyms: EDG3, Endothelial differentiation G-protein coupled receptor 3, FLJ37523, FLJ93220, LPB3, MGC71696, S1P receptor 3, S1PR3, Sphingosine 1-phosphate receptor 3

Molekulargewicht: approx. 42 kDa

Gen-ID: 1903

NCBI Accession: NP_005217

UniProt: Q99500