CHRM5 Antikörper

Produktnummer ABIN317740

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CHRM5 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für CHRM5 Antikörper (ABIN317740)

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CHRM5 Antikörper

Spezifität: MAChR M5 antibody detects endogenous levels of mAChR M5 protein.(region surrounding Pro224)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Affinity-chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CHRM5

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Andere Bezeichnung: Muscarinic Acetylcholine Receptor M5

Hintergrund: The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.Synonyms: CHRM5, mAChR M5, mAChR-M5

Molekulargewicht: approx. 45 kDa

Gen-ID: 1133

NCBI Accession: NP_036257

UniProt: P08912

Pathways: Synaptic Membrane