ADORA1 Antikörper

Produktnummer ABIN317738

Der Kaninchen Polyklonal anti-ADORA1 Antikörper wird verwendet zum Nachweis von ADORA1 in Proben von Human und Maus. Er wurde validiert für WB, IF und EIA.

Kurzübersicht für ADORA1 Antikörper (ABIN317738)

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADORA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-ADORA1 Antikörper

Spezifität: This antibody detects endogenous levels of Adenosine A1-R protein.(region surrounding Leu591)

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ADORA1

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Andere Bezeichnung: Adenosine Receptor A1

Hintergrund: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA1

Molekulargewicht: approx. 37 kDa

Gen-ID: 134

NCBI Accession: NP_000665

UniProt: P30542

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Synaptic Membrane