CasLTR2 Antikörper

Produktnummer ABIN317732

Der Kaninchen Polyklonal anti-CasLTR2 Antikörper wird verwendet zum Nachweis von CasLTR2 in Proben von Human. Er wurde validiert für WB, IF und EIA.

Kurzübersicht für CasLTR2 Antikörper (ABIN317732)

Target: CasLTR2 (CYSLTR2) (Cysteinyl Leukotriene Receptor 2 (CYSLTR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CasLTR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-CasLTR2 Antikörper

Spezifität: This antibody detects endogenous levels of CYSLTR2 protein(region surrrounding His324).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity-chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CasLTR2

Target: CasLTR2 (CYSLTR2) (Cysteinyl Leukotriene Receptor 2 (CYSLTR2))

Andere Bezeichnung: CYSLTR2

Hintergrund: Cysteinyl leukotriene (CysLTs) induce intracellular calcium mobilization through the binding of two distinct seven-transmembrane, G protein-coupled receptors, designated CysLT1 Receptor and CysLT2 Receptor, to induce potent bronchoconstriction. Airway smooth muscle and macrophages express both receptor types, and additionally monocytes and eosinophils express CysLT1 Receptor, while cardiac Purkinje cells, adrenal medulla, peripheral blood leukocytes and brain also utilize CysLT2 Receptor. The effects of the CysLT Receptors can be blocked by antagonists, indicating a therapeutic mechanism for the treatment of asthma and allergies.Synonyms: CYSLT2, CysLTR2, Cysteinyl leukotriene receptor 2, G-protein coupled receptor GPCR21, G-protein coupled receptor HG57, HG57, HPN321, hGPCR21

Molekulargewicht: approx. 40 kDa

Gen-ID: 57105

NCBI Accession: NP_065110

UniProt: Q9NS75