HTR2C Antikörper

Produktnummer ABIN317726

Produktdetails anti-HTR2C Antikörper

Target: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTR2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects endogenous levels of SR-2C protein.(region surrounding Gln437)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.3 with 0.05 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HTR2C

Target: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Andere Bezeichnung: Serotonin Receptor 2C (HTR2C) (HTR2C Produkte)

Synonyme: 5-HT2C antikoerper, 5-HTR2C antikoerper, HTR1C antikoerper, 5-HT2cR antikoerper, 5HT1c antikoerper, Htr1c antikoerper, SR1 antikoerper, 5HT-1C antikoerper, 5HT2C antikoerper, 5-HT-2C antikoerper, 5-ht2cr antikoerper, si:dkey-24g18.2 antikoerper, 5ht2c antikoerper, 5HTR2C antikoerper, 5-hydroxytryptamine receptor 2C antikoerper, 5-hydroxytryptamine (serotonin) receptor 2C antikoerper, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog antikoerper, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 antikoerper, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antikoerper, HTR2C antikoerper, Htr2c antikoerper, htr2c.S antikoerper, htr2cl1 antikoerper, LOC407134 antikoerper

Hintergrund: The members of the G protein coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Members of the β-Arrestin family regulate receptor binding to G proteins. β-Arrestins have been found to be located at postsynaptic sites, where they are thought to act in concert with βARK (βARK1, also designated GRK 2, or βARK2, also designated GRK 3) to regulate G protein-coupled neurotransmitter receptors. Expression of β- Arrestin-1 and b-Arrestin-2 is seen predominantly in spleen and neuronal tissues. It has been shown that β-Arrestin-1 expression is modulated by intracellular cAMP, which may be a novel mechanism for the regulation of receptor- mediated responses.Synonyms: 5-HT-2C, 5-HT2C, 5-HTR2C, 5-hydroxytryptamine receptor 2C, 5HT-1C, HTR1C

Molekulargewicht: approx. 55 kDa

Gen-ID: 3358

NCBI Accession: NP_000859

UniProt: P28335

Pathways: Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour