HNRNPM Antikörper

Produktnummer ABIN317716

Produktdetails anti-HNRNPM Antikörper

Target: HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of hnRNP- M / HNRNPM (region surrounding Pro43).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity-chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HNRNPM

Target: HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

Andere Bezeichnung: HnRNP-M / HNRNPM (HNRNPM Produkte)

Synonyme: HNRPM antikoerper, si:ch211-197g15.1 antikoerper, wu:fa10g07 antikoerper, wu:fa98b02 antikoerper, hnrpm antikoerper, CG9373 antikoerper, Dmel\\CG9373 antikoerper, Hrp59 antikoerper, cg9373 antikoerper, hnRNP M antikoerper, hrp59 antikoerper, p75 antikoerper, CEAR antikoerper, HNRNPM4 antikoerper, HNRPM4 antikoerper, HTGR1 antikoerper, NAGR1 antikoerper, 2610023M21Rik antikoerper, AA409009 antikoerper, Hnrpm antikoerper, mKIAA4193 antikoerper, Hnrpm4 antikoerper, heterogeneous nuclear ribonucleoprotein M antikoerper, Heterogeneous nuclear ribonucleoprotein M antikoerper, rumpelstiltskin antikoerper, HNRNPM antikoerper, hnrnpm antikoerper, hnrpm antikoerper, rump antikoerper, Hnrnpm antikoerper

Hintergrund: Proteins that directly bind to nascent RNA polymerase II transcripts, the heterogenous nuclear ribonucleoproteins (hnRNPs), play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. A group of abundant hnRNPs, the M1-M4 proteins, appear as a cluster of four proteins. The M proteins are pre-mRNA binding proteins in vivo, and they bind avidly to poly (G) and poly (U) RNA homopolymers in vitro. M proteins are members of the ribonucleoprotein consensus sequence family of RNA-binding proteins with greatest similarity to a hypothetical RNA-binding protein from Saccharomyces cerevisiae. The M proteins also possess an unusual hexapeptide-repeat region rich in methionine and arginine residues (MR repeat motif) that resembles a repeat in the 64 kDa subunit of cleavage stimulation factor, which is involved in 3'-end maturation of pre-mRNAs. Proteins immunologically related to M exist in divergent eukaryotes ranging from human to yeast.Synonyms: HNRPM, Heterogeneous nuclear ribonucleoprotein M, NAGR1

Molekulargewicht: approx. 85 kDa

Gen-ID: 4670

NCBI Accession: NP_005959

UniProt: P52272