MC1 Receptor Antikörper

Produktnummer ABIN317707

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MC1 Receptor in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MC1 Receptor Antikörper (ABIN317707)

Target: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MC1 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-MC1 Receptor Antikörper

Spezifität: This antibody detects endogenous levels of MC1-R protein (region surrounding Val312).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MC1 Receptor

Target: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Andere Bezeichnung: MC1-R

Hintergrund: The melanocortin family comprises the alpha-, beta- and gamma-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.Synonyms: MC1R, MSH-R, MSHR, Melanocortin receptor 1, Melanocyte-stimulating hormone receptor, Melanotropin receptor

Molekulargewicht: approx. 35 kDa

Gen-ID: 4157

NCBI Accession: NP_002377

UniProt: Q01726

Pathways: cAMP Metabolic Process, Feeding Behaviour