HRH1 Antikörper

Produktnummer ABIN317706

Dieses Anti-HRH1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HRH1 in WB, IF und EIA. Geeignet für Human.

Kurzübersicht für HRH1 Antikörper (ABIN317706)

Target: HRH1 (Histamine Receptor H1 (HRH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-HRH1 Antikörper

Spezifität: This antibody detects endogenous levels of Histamine H1 Receptor protein.(region surrounding Lys179)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 1000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HRH1

Target: HRH1 (Histamine Receptor H1 (HRH1))

Andere Bezeichnung: Histamine H1 Receptor

Hintergrund: Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors, the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H1 Receptor maps to chromosome 3p25 and is expressed in highest abundance in placenta, with lower levels in lung, skeletal muscle, kidney and brain. The murine Histamine H2 Receptor gene maps to chromosome 13 and is highly expressed in stomach with moderate expression in brain and heart. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus. The human Histamine H4 Receptor gene maps to chromosome 18q11 and is expressed most abundantly in bone marrow and spleen in addition to peripheral blood leukocytes, thymus, small intestine and colon.Synonyms: HR-H1, HRH1, Histamine H1 receptor

Molekulargewicht: approx. 60 kDa

Gen-ID: 3269

NCBI Accession: NP_000852

UniProt: P35367

Pathways: Regulation of Carbohydrate Metabolic Process