CHRM1 Antikörper

Produktnummer ABIN317696

Der Kaninchen Polyklonal Anti-CHRM1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, CHRM1 in Proben von Ratte, Human und Maus zu detektieren.

Kurzübersicht für CHRM1 Antikörper (ABIN317696)

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CHRM1 Antikörper

Spezifität: This antibody detects endogenous levels of Muscarinic acetylcholine receptor M1 / mAChR M1 protein (region surrounding Arg336).

Aufreinigung: Affinity-chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CHRM1

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Andere Bezeichnung: Muscarinic Acetylcholine Receptor M1

Hintergrund: The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.Synonyms: CHRM1, mAChR M1, mAChR-M1

Molekulargewicht: Approx. 50 kDa

Gen-ID: 1128

NCBI Accession: NP_000729

UniProt: P11229

Pathways: Synaptic Membrane