Adenosine A2b Receptor Antikörper

Produktnummer ABIN317695

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Adenosine A2b Receptor in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Adenosine A2b Receptor Antikörper (ABIN317695)

Target: Adenosine A2b Receptor (ADORA2B)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenosine A2b Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-Adenosine A2b Receptor Antikörper

Spezifität: This antibody detects endogenous levels of Adenosine A2B-R protein.(region surrounding Trp270)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1/5000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Adenosine A2b Receptor

Target: Adenosine A2b Receptor (ADORA2B)

Andere Bezeichnung: Adenosine Receptor A2b

Hintergrund: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R, and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA2B

Molekulargewicht: approx. 34 kDa

Gen-ID: 136

NCBI Accession: NP_000667

UniProt: P29275

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process