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TACC3 Antikörper

TACC3 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN317622
  • Target Alle TACC3 Antikörper anzeigen
    TACC3 (Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3))
    Reaktivität
    • 42
    • 21
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 36
    • 5
    • 1
    Kaninchen
    Klonalität
    • 27
    • 15
    Polyklonal
    Konjugat
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser TACC3 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 12
    • 12
    • 11
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of TACC3 protein.(region surrounding Thr813)
    Aufreinigung
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product TACC3 Primärantikörper
  • Applikationshinweise
    ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TACC3 (Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3))
    Andere Bezeichnung
    TACC3 / ERIC1 (TACC3 Produkte)
    Synonyme
    Aint antikoerper, C86661 antikoerper, Eric1 antikoerper, ERIC-1 antikoerper, ERIC1 antikoerper, maskin antikoerper, masking antikoerper, xmaskin antikoerper, transforming, acidic coiled-coil containing protein 3 antikoerper, transforming acidic coiled-coil containing protein 3 antikoerper, transforming acidic coiled-coil containing protein 3 S homeolog antikoerper, Tacc3 antikoerper, TACC3 antikoerper, tacc3.S antikoerper
    Hintergrund
    TACC1 (transforming acidic coiled coil gene 1) is one of three TACC family members, which are thought to be involved in breast tumorigenesis. TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15 % of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.Synonyms: ERIC-1, Transforming acidic coiled-coil-containing protein 3
    Gen-ID
    10460
    NCBI Accession
    NP_006333
    UniProt
    Q9Y6A5
    Pathways
    Maintenance of Protein Location
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