STEAP1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA. Western blot (cell lysates of LNcap (30 μg) and Rat testis (30 μg) were resolved bySDS-PAGE, transferred to NC membrane and probed with anti-human STEAP1 (1: 500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRPand an ECL detection system). Immunofluorescence (1: 100 - 1: 300). Immunohistochemsitry on paraffin sections (1: 50 - 1: 100). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1.0 mg/mL
Buffer
PBS, pH 7.4, 0.09 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
STEAP1
(Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
PRSS24 antikoerper, STEAP antikoerper, STEAP1 antikoerper, 2410007B19Rik antikoerper, Prss24 antikoerper, Steap antikoerper, STEAP family member 1 antikoerper, six transmembrane epithelial antigen of the prostate 1 antikoerper, STEAP1 antikoerper, Steap1 antikoerper
Hintergrund
Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewing's sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy. NCBI Accession No: NP_036581Synonyms: Metalloreductase STEAP1, PRSS24, STEAP-1, Six-transmembrane epithelial antigen of prostate 1