SIGLEC7 Antikörper

Produktnummer ABIN316978

Der Maus Monoklonal anti-SIGLEC7 Antikörper (Klon 30-04-86) (ABIN316978) detektiert spezifisch SIGLEC7 in FACS und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SIGLEC7 Antikörper (ABIN316978)

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIGLEC7 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 30-04-86

Produktdetails anti-SIGLEC7 Antikörper

Spezifität: This antibody is specific for CDw328.

Produktmerkmale: Synonyms: Siglec-7, QA79 membrane protein, p75, D-siglec, CDw328, AIRM1, Sialic acid-binding Ig-likelectin 7, Adhesion inhibitory receptor molecule 1

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Monocyte-derived dendritic cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 1/100 - 1/200. Immunohistochemistry on frozen sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Haltbarkeit: 12 months

Details zu SIGLEC7

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Andere Bezeichnung: CD328 / SIGLEC7

Hintergrund: CDw328 is a type I transmembrane glycoprotein and member of the Siglec (sialic acid binding Ig-like lectin) family, designated Siglec-7, originally identified as an inhibitory NK cell receptor (NKR) and negative regulator of NK activation, attributed to ITIM recruitment of SHP-1 phosphatase. CDw328 is expressed predominantly by natural killer cells (NK) and to a lesser extent by monocytes and granulocytes and, like Siglec-5 (CD170), has been shown to bind to sialylated ligands of targets through recognition of sialic acid in both the alpha-2,3- and alpha-2,6- glycosidic linkage.Synonyms: AIRM1, Adhesion inhibitory receptor molecule 1, CDw328, D-siglec, QA79 membrane protein, Sialic acid-binding Ig-like lectin 7, Siglec-7, p75

Gen-ID: 27036

UniProt: Q9Y286