This antibody is specific for the C-terminal variant of human CDw92 (isoform 3), also known as CTL1. Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.
Produktmerkmale
Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1
Aufreinigung
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
SLC44A1
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Flow Cytometry: 1/10. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Reconstitute with 1.0 mL distilled water
Konzentration
0,1 mg/mL
Buffer
Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3) and 1 % Bovine Serum Albumin
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
SLC44A1
(Solute Carrier Family 44, Member 1 (SLC44A1))
CD92 antikoerper, CDW92 antikoerper, CHTL1 antikoerper, CTL1 antikoerper, RP11-287A8.1 antikoerper, Cdw92 antikoerper, Ctl1 antikoerper, 2210409B22Rik antikoerper, 4833416H08Rik antikoerper, AW547365 antikoerper, SLC44A1 antikoerper, slc44a1 antikoerper, zgc:112201 antikoerper, ctl1 antikoerper, solute carrier family 44 member 1 antikoerper, solute carrier family 44, member 1 antikoerper, solute carrier family 44 (choline transporter), member 1a antikoerper, solute carrier family 44 (choline transporter), member 1 antikoerper, choline transporter-like protein 1 antikoerper, Choline transporter-like protein 1 antikoerper, solute carrier family 44 (choline transporter), member 1 L homeolog antikoerper, SLC44A1 antikoerper, Slc44a1 antikoerper, slc44a1a antikoerper, slc44a1 antikoerper, LOC100404101 antikoerper, chtl-1 antikoerper, slc44a1.L antikoerper
Hintergrund
CDw92 is a 70 kDa multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine.Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1