This antibody is specific for the C-terminal variant of Human CDw92 (isoform 3), also known as CTL1. Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10. Removal of Sodium Azide is recommended prior to use in Functional Assays.
Produktmerkmale
Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1
Aufreinigung
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
SLC44A1
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Flow Cytometry: 1/5. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0,1 mg/mL
Buffer
PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
SLC44A1
(Solute Carrier Family 44, Member 1 (SLC44A1))
CDw92 is a 70 kDa multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine.Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1