CD81 Antikörper (PE)

Produktnummer ABIN307700

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD81 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD81 Antikörper (PE) (ABIN307700)

Target: CD81

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: Eat2

Produktdetails anti-CD81 Antikörper (PE)

Spezifität: Reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and NK cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells

Aufreinigung: Purified

Immunogen:

Type of Immunogen: Native protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, EIA grade BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81

Hintergrund: Name/Gene ID: CD81
Family: Tetraspan

Synonyms: CD81, CD81 antigen, CD81 Molecule, CVID6, S5.7, TAPA1, TAPA-1, Tetraspanin-28, TSPAN28, Tspan-28

Gen-ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C