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Netrin 1 Antikörper

NTN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN307033
  • Target Alle Netrin 1 (NTN1) Antikörper anzeigen
    Netrin 1 (NTN1)
    Reaktivität
    • 47
    • 43
    • 35
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 56
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 61
    • 9
    Polyklonal
    Konjugat
    • 39
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Netrin 1 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 22
    • 20
    • 13
    • 13
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Cat, Rind (Kuh), Human, Makake, Maus, Ratte
    Produktmerkmale
    Netrin 1, NTN1,Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis. Netrin 1s main receptor is DCC (deleted in colorectal cancer- a putative tumor suppressor gene whose expression is lost in numerous cancers). DCC belongs to the so-called family of dependence receptors. These receptors induce apoptosis when their ligand is absent, thus conferring a state of cellular dependence on Netrin 1 availability. The DCC/netrin-1 duo regulates neuron survival during nervous system development. The mechanism(s) by which Netrin 1/ DCC triggers cell death are still unknown. The localization of DCC to lipid rafts appears to be a prerequisite for its proapoptotic activity.
    Aufreinigung
    Ammonium Sulfate Precipitation
    Immunogen
    Synthetic peptide derived from the human Netrin 1 protein
    Isotyp
    IgG
    Top Product
    Discover our top product NTN1 Primärantikörper
  • Applikationshinweise
    Antibody can be used for Western blotting (0.5-2 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • Target
    Netrin 1 (NTN1)
    Andere Bezeichnung
    Netrin 1 (NTN1 Produkte)
    Synonyme
    ntn1-A antikoerper, Netrin-1 antikoerper, NTN1 antikoerper, unc-6 antikoerper, MGC147073 antikoerper, NTN1L antikoerper, AI561871 antikoerper, BC019633 antikoerper, netrin-1 antikoerper, netrin 1 L homeolog antikoerper, netrin 1 antikoerper, ntn1.L antikoerper, NTN1 antikoerper, ntn1 antikoerper, Ntn1 antikoerper
    NCBI Accession
    NP_004813
    Pathways
    Regulation of Cell Size
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