SPTLC1 Antikörper
Kurzübersicht für SPTLC1 Antikörper (ABIN307030)
Target
Alle SPTLC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Rabbit anti Human Serine Palmitoyltransferase 1
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Kreuzreaktivität
- Human
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Produktmerkmale
- Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.
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Aufreinigung
- Ammonium Sulfate Precipitation
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Immunogen
- Synthetic peptide derived from the human serine palmitoyltransferase enzyme.
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Isotyp
- IgG
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Applikationshinweise
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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Andere Bezeichnung
- Serine Palmitoyltransferase 1
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Hintergrund
- Long chain base biosynthesis protein 1, LCB-1, LCB1, Serine-palmitoyl-CoA transferase 1, SPT1, SPT 1, SPT-1
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UniProt
- O15269
Target
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