Sphingomyelin Synthase 1 Antikörper
Kurzübersicht für Sphingomyelin Synthase 1 Antikörper (ABIN306949)
Target
Alle Sphingomyelin Synthase 1 (SGMS1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Rabbit anti Human Sphingomyelin Synthase 1 (Peptide as antigen)
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Produktmerkmale
- A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus, Golgi membrane, multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.
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Aufreinigung
- High Salt Precipitation
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Applikationshinweise
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/ml
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Sphingomyelin Synthase 1 (SGMS1)
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Andere Bezeichnung
- Sphingomyelin Synthase 1
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Hintergrund
- Phosphatidylcholine:ceramide cholinephosphotransferase 1 Transmembrane protein 23, Sphingomyelin synthase 1, Mob protein
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UniProt
- Q86VZ5
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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