Der Kaninchen Polyklonal Anti-Tumor Protein p73-Antikörper wurde für WB und IP validiert. Er ist geeignet, Tumor Protein p73 in Proben von Human zu detektieren.
The p73 exhibits sequence homology to the p53's transcriptional activation, DNA binding, and oligomerization domains. However, adenovirus E1B 55K, simian virus 40 T, and human papillomavirus E6 do not physically interact with p73 indicating that the functions of these two proteins may differ under physiological conditions. p73 is expressed in either a full-length form ( ) (MW ~80 kDa) or a shorter ( ) (MW ~70 kDa) mRNA variant, with exon 13 spliced out.
Aufreinigung
Ammonium Sulfate Precipitation
Immunogen
GST-fused recombinant protein derived from the C terminal of the p73 protein.