Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) (N-Term) Antikörper

Produktnummer ABIN306909

Der Kaninchen Polyklonal anti-Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) Antikörper (ABIN306909) detektiert spezifisch Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) (N-Term) Antikörper (ABIN306909)

Target: Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: N-Term

Verwendungszweck: Rabbit anti Human Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) CT

Kreuzreaktivität: Human

Produktmerkmale: EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG4 is lysophospholipid. There are 6 known members of the EDG receptor family and they are implicated in mediating growthrelated effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor and leukocyte containing tissues.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Antibody raised against a unique synthetic peptide derived from the N-terminal of the human EDG4 protein. Antigen sequence differs in mouse and rat by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This antibody can be used for Western blotting (5-10 μg/mL). Western blot should be visualized using a high sensitivity secondary/substrate system (i.e. Pierce's SuperSignal West Femto Maximum Sensitivity Substrate). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Antigendetails

Target: Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4)

UniProt: Q9HBW0