PP5.2 Antikörper (C-Term)

Produktnummer ABIN306896

Der Kaninchen Polyklonal Anti-PP5.2-Antikörper wurde für WB validiert. Er ist geeignet, PP5.2 in Proben von Human zu detektieren.

Kurzübersicht für PP5.2 Antikörper (C-Term) (ABIN306896)

Target: PP5.2 (Serine/threonine-Protein Phosphatase 5 (PP5.2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PP5.2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PP5.2 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human

Produktmerkmale: Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PP-T) (PPT), PPP5C, PPP5,Protein phosphatase 5 (PP5) is a novel human protein serine/threonine phosphatase of molecular weight of 58 kDa. It is made up of a C-terminal phosphatase catalytic domain and an N-terminal domain, which has four repeats of 34 amino acids, three of which are tandemly arranged. The phosphatase domain contains all of the invariant motifs of the PP1/PP2A/PP2B gene family. However, it is not closely related to any other known member of this family of phosphatases. Thus it makes up a new subfamily of phosphatases. PP5 expressed in bacteria has been shown to dephosphorylate serine residues in proteins and is more sensitive than PP1 to the tumor promoter okadaic acid. PP5 appears to be localized to the nucleus suggesting that, like other nuclear tetratricopeptide (TPR)-containing proteins, it may playa role in the regulation of RNA biogenesis and mitosis.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Rabbits were immunized with a Synthetic peptide derived from the human protein phosphatase 5 proteins

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This antibody can be used for Western blotting (5-10 μg/mL). Other applications being evaulated. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu PP5.2

Target: PP5.2 (Serine/threonine-Protein Phosphatase 5 (PP5.2))

Andere Bezeichnung: Protein Phosphatase 5