SMC2 Antikörper (AA 523-768)

Produktnummer ABIN306862

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SMC2 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SMC2 Antikörper (AA 523-768) (ABIN306862)

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SMC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: E1M

Produktdetails anti-SMC2 Antikörper

Bindungsspezifität: AA 523-768

Kreuzreaktivität: Human

Produktmerkmale: CAP-E, Structural maintenance of chromosomes protein 2, SMC-2,CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.

Aufreinigung: Protein A/G Chromatography

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant protein corresponding to amino acids 523-768 of human CAP-E and mouse myeloma cells.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Andere Bezeichnung: Chromosome Associated Protein-E

UniProt: O95347