Kein (4,5,6,8,10,13,18) Antikörper

Produktnummer ABIN306826

Dieser Maus Monoklonal Antikörper detektiert spezifisch Kein (4,5,6,8,10,13,18) in IHC (fro), IHC (p) und WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Kein (4,5,6,8,10,13,18) Antikörper (ABIN306826)

Target: Kein (4,5,6,8,10,13,18)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Klon: C11

Produktdetails

Verwendungszweck: Mouse anti Human Keratin (4,5,6,8,10,13,18)

Kreuzreaktivität: Human

Produktmerkmale: Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non-keratinizing cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.

Aufreinigung: Purified by saturated ammonium sulphate precipitation

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: X1260M detects keratins 4,5,6,8,10,13 & 18 by Western blot. Immunohistochemistry can be performed on frozen tissues and paraffin sections. Optimal concentration should be evaluated by serial dilutions. X1260M reacts with a variety of normal and neoplastic epithelia. Reacting with simple epithelium and both basal and superbasal layers of cornifying and non-cornifying squamous epithelium this antibody is also useful in staining cultured epithelial cell lines. It is useful in differentiating epithelial tumors from non-epithelial tumors.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Antigendetails

Target: Kein (4,5,6,8,10,13,18)

UniProt: P13647