Kein 7 Antikörper

Produktnummer ABIN306824

Der Maus Monoklonal anti-Kein 7 Antikörper wird verwendet zum Nachweis von Kein 7 in Proben von Human. Er wurde validiert für IHC (fro) und WB.

Kurzübersicht für Kein 7 Antikörper (ABIN306824)

Target: Kein 7

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)

Klon: C35

Produktdetails

Verwendungszweck: Mouse anti Human Keratin 7

Kreuzreaktivität: Human

Produktmerkmale: Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non-keratinizing cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification. Cytokeratin 7 is a basic cytokeratin which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of the ovary, lung and breast but not colon or gastrointestinal tract.

Aufreinigung: Protein A/G Chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Detects keratin 7 by Western blot. Detects a 54 kDa band corresponding to keratin 7. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Antigendetails

Target: Kein 7

UniProt: P08729