VSX2 Antikörper (N-Term)

Produktnummer ABIN306799

Produktdetails anti-VSX2 Antikörper

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser VSX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Human Chx10 protein

Kreuzreaktivität: Huhn, Human, Maus, Ratte

Produktmerkmale: Ceh-10 homeodomain-containing homolog,Chx10 is a 46 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in Chx10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina Chx10 is expressed in retinal progenitors, while in the mature retina, Chx10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the Chx10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. Chx10 is also expressed in the developing brainstem, thalamus, and spinal cord.

Immunogen: Antibody raised in sheep against a recombinant protein corresponding to amino acids 1 to 131 derived from the N-terminal region of the human Chx10 protein conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Detects Chx10 by Western blot at 0.5 to 1 μg/mL. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Optimal concentration should be evaluated by serial dilutions. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Ammonium sulphate precipitated antibody in PBS with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu VSX2

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Andere Bezeichnung: chx 10 (NT) (VSX2 Produkte)

Synonyme: CHX10 antikoerper, HOX10 antikoerper, MCOP2 antikoerper, MCOPCB3 antikoerper, RET1 antikoerper, Chx10 antikoerper, Hox-10 antikoerper, Hox10 antikoerper, or antikoerper, VSX2 antikoerper, Vsx-2 antikoerper, alx antikoerper, chx10 antikoerper, c-ret antikoerper, cret antikoerper, etID315074.13 antikoerper, ret1 antikoerper, wu:fd13h01 antikoerper, visual system homeobox 2 antikoerper, ret proto-oncogene receptor tyrosine kinase antikoerper, Vsx2 transcription factor antikoerper, VSX2 antikoerper, Vsx2 antikoerper, vsx2 antikoerper, ret antikoerper

UniProt: P58304

Pathways: Dopaminergic Neurogenesis