VSX2 Antikörper

Produktnummer ABIN306799

Dieser Schaf Polyklonal Antikörper detektiert spezifisch VSX2 in WB und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Huhn.

Kurzübersicht für VSX2 Antikörper (ABIN306799)

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser VSX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-VSX2 Antikörper

Verwendungszweck: Sheep anti Human chx 10 (Visual system homeobox 2) (NT)

Spezifität: Human Chx10 protein

Kreuzreaktivität: Huhn, Human, Maus, Ratte

Produktmerkmale: Chx10 is a 46 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in Chx10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina Chx10 is expressed in retinal progenitors, while in the mature retina, Chx10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the Chx10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. Chx10 is also expressed in the developing brainstem, thalamus, and spinal cord.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Detects Chx10 by Western blot at 0.5 to 1 μg/mL. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Optimal concentration should be evaluated by serial dilutions. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu VSX2

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Andere Bezeichnung: chx 10 (NT)

Hintergrund: Ceh-10 homeodomain-containing homolog

Molekulargewicht: 46kDa

UniProt: P58304

Pathways: Dopaminergic Neurogenesis