ARHGEF2 Antikörper

Produktnummer ABIN306728

Der Schaf-Polyklonal Anti-ARHGEF2-Antikörper wurde für WB, IF und IP validiert. Er ist geeignet zum Nachweis von ARHGEF2 in Proben aus Maus. }

Kurzübersicht für ARHGEF2 Antikörper (ABIN306728)

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Reaktivität: Maus

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-ARHGEF2 Antikörper

Kreuzreaktivität: Maus

Produktmerkmale: Rho guanine nucleotide exchange factor 2, ARHGEF2,Lfc is a 118 kDa protein discovered in a screen for oncogenes in NIH 3T3 cells. Lfc is a signaling protein related to Lbc and is part of the Dbl family of proteins. Lfc is a guanine-nucleotide exchange factor (GEF) for the Rho family of small GTPases. Lfc has also been shown to be upstream of the serine-threonine kinase JNK. Lfc has also been shown to mediate the activation of the Rac signaling pathway.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Antibody developed using protein corresponding to amino acids 2 to 447 of the Lfc protein fused to GST.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Detects Lfc in mouse tissues by immunoprecipitation-Western blot at 4 μg/mL. Detects a 118 kDa band in mouse tissue extracts corresponding to wild-type Lfc. Can also be used in immunofluorescence assays. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu ARHGEF2

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Andere Bezeichnung: LFC

Pathways: Negative Regulation of intrinsic apoptotic Signaling