Der Kaninchen Polyklonal anti-Potassium Channel Antikörper wird verwendet zum Nachweis von Potassium Channel in Proben von Ratte. Er wurde validiert für WB, IF und IP.
Kurzübersicht für Potassium Channel Antikörper (ABIN306719)
Target
Potassium Channel
Reaktivität
Ratte
Wirt
Kaninchen
Klonalität
Polyklonal
Konjugat
Unkonjugiert
Applikation
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
Verwendungszweck
Rabbit anti Rat Potassium Channel
Kreuzreaktivität
Ratte
Produktmerkmale
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to Icurrent in heart and current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits In response to membrane depolarization, Kv4.2 channels accumulate in the closed-inactivated state(s), from which they directly recover, bypassing the open state. Kv4.2 is a substrate for ERK in vitro and in vivo, and suggest that ERK may regulate potassium-channel function by direct phosphorylation of the pore-forming alpha subunit.
Optimal antibody concentration should be evaluated by serial dilutions. Suggested Western Blot dilution 1:1000. Other applications: Immunoprecipitation, immunofluorescence.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
phosphate buffered saline with 0.08 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Target
Potassium Channel
Hintergrund
RK5, Shal1, Kcnd2, Potassium voltage-gated channel subfamily D member 2