Potassium Channel Antikörper
Kurzübersicht für Potassium Channel Antikörper (ABIN306719)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Rabbit anti Rat Potassium Channel
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Kreuzreaktivität
- Ratte
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Produktmerkmale
- Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to Icurrent in heart and current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits In response to membrane depolarization, Kv4.2 channels accumulate in the closed-inactivated state(s), from which they directly recover, bypassing the open state. Kv4.2 is a substrate for ERK in vitro and in vivo, and suggest that ERK may regulate potassium-channel function by direct phosphorylation of the pore-forming alpha subunit.
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Aufreinigung
- Ammonium Sulfate Precipitation
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Isotyp
- IgG
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Applikationshinweise
- Optimal antibody concentration should be evaluated by serial dilutions. Suggested Western Blot dilution 1:1000. Other applications: Immunoprecipitation, immunofluorescence.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Potassium Channel
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Hintergrund
- RK5, Shal1, Kcnd2, Potassium voltage-gated channel subfamily D member 2
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UniProt
- Q63881
Target
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