CAPN1 Antikörper
Kurzübersicht für CAPN1 Antikörper (ABIN306692)
Target
Alle CAPN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Mouse anti Human Calpain I, II (small subunit)
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Kreuzreaktivität
- Rind (Kuh), Human
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Produktmerkmale
- The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and μ-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, μ-calpain is active at micromolar (μM) concentrations of Ca ++. In addition to the ubiquitously expressed m- and μcalpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
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Aufreinigung
- Protein A/G Chromatography
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Isotyp
- IgG1
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Applikationshinweise
- Use at 0.5-1 μg/mL for ELISA and western blot, 1-2 μg/mL for immunoprecipitation.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CAPN1 (Calpain 1 (CAPN1))
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Andere Bezeichnung
- Calpain I
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Hintergrund
- Mouse anti calpain I, II small subunit, p30
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UniProt
- P17655
Target
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